Utilization of biological variation data in the interpretation of laboratory test results – survey about clinicians’ opinion and knowledge     

Humeyra Ozturk Emre  Fatma Hande Karpuzoglu  Cihan Coskun  Ebru Demirel Sezer  Ozlem Goruroglu Ozturk  Fatma Ucar  Hikmet Can Cubukcu  Fatma Demet Arslan  Levent Deniz  Mehmet Senes  Mustafa Serteser  Cevat Yazici  Dogan Yucel  Abdurrahman Coskun 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2021,31(1)

IntroductionTo interpret test results correctly, understanding of the variations that affect test results is essential. The aim of this study is: 1) to evaluate the clinicians’ knowledge and opinion concerning biological variation (BV), and 2) to investigate if clinicians use BV in the interpretation of test results.Materials and methodsThis study uses a questionnaire comprising open-ended and close-ended questions. Questions were selected from the real-life numerical examples of interpretation of test results, the knowledge about main sources of variations in laboratories and the opinion of clinicians on BV. A total of 399 clinicians were interviewed, and the answers were evaluated using a scoring system ranked from A (clinician has the highest level of knowledge and the ability of using BV data) to D (clinician has no knowledge about variations in laboratory). The results were presented as number (N) and percentage (%).ResultsAltogether, 60.4% of clinicians have knowledge of pre-analytical and analytical variations; but only 3.5% of them have knowledge related to BV. The number of clinicians using BV data or reference change value (RCV) to interpret measurements results was zero, while 79.4% of clinicians accepted that the difference between two measurements results located within the reference interval may be significant.ConclusionsClinicians do not use BV data or tools derived from BV such as RCV to interpret test results. It is recommended that BV should be included in the medical school curriculum, and clinicians should be encouraged to use BV data for safe and valid interpretation of test results.  相似文献   

How to deal with OCD: a 5-step,CBT-based plan for overcoming obsessive-compulsive disorder     

Mehmet Agdiran 《Educational Psychology in Practice》2017,33(1)

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A survey of health information seeking by cancer patients indicates some problems over medical explanations and terminology     

Mahmut Akbolat PhD  Mustafa Amarat PhD  Özgün Ünal PhD  Gülcan Şantaş PhD 《Health information and libraries journal》2023,40(1):29-41

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Fostering Continuous Improvement and Learning Through Peer Assessment: Part of an Integral Model of Assessment     

Nancy T. Davis  Evrim Genc Kumtepe  Mehmet Aydeniz 《Educational Assessment》2013,18(2):113-135

Assessment is a critical component of educational practices and thus impacts educational reform efforts. This article reviews and considers assessment from 2 perspectives: a focus on accountability and a focus on continuous improvement. A class of preservice and practicing science teachers explored notions of assessment while experiencing peer assessment as part of the class. Their online conversations about the processes of establishing quality criteria for peer assessment and their reflections on the experiences compose the primary data source. Two purposes for assessment, accountability and continuous improvement, arose from the data and created conflicts within the individuals and the class. To resolve this conflict, we propose a framework for viewing assessment as part of an integral model (Wilber, 2004 Wilber, K. 2004. Kosmic consciousness [CD], Boulder, CO: Sounds True..  [Google Scholar]) that includes and transcends the dualities.  相似文献   

The use of twitter by mayors in Turkey: Tweets for better public services?     

Mehmet Zahid Sobaci  Naci Karkin 《Government Information Quarterly》2013

This article aims to provide an overall picture of the use of Twitter as a significant social media tool by mayors in Turkey and to investigate, using content analysis and tweet categorization, whether Twitter is used by mayors in Turkey to offer better public services. Thus, this study focuses on the impact of Twitter in Turkey on transparent, participatory and citizen-oriented local public services. Our analysis has revealed that mayors in Turkey use Twitter especially to share information, send personal messages and share their location and activities. The use of Twitter for transparent, participatory and citizen-oriented public service delivery is not common among mayors. Twitter is adopted and used by mayors mostly for the purposes of self-promotion and political marketing in Turkey.  相似文献   

The effect of storage time and freeze-thaw cycles on the stability of serum samples     

Serap Cuhadar  Mehmet Koseoglu  Aysenur Atay  Ahmet Dirican 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2013,23(1):70-77

Introduction:

Optimal storage of serum specimens in central laboratories for a long period for multicenter reference interval studies, or epidemiologic studies remains to be determined. We aimed to examine the analytical stability of chemistry analytes following numerous freeze-thaw and long term storage.

Materials and methods:

Serum samples were obtained from 15 patients. Following baseline measurement, sera of each subject were aliquoted and stored at −20 °C for two experiments. A group of sera were kept frozen for up to 1, 2 and 3 months and then analyzed for stability. The other experiment consisted of one to ten times of freeze and thaw cycles. Total of 17 chemistry analytes were assayed at each time point. The results were compared with those obtained from the initial analysis of fresh samples. Median or mean changes from baseline (T₀) concentrations were evaluated both statistically and clinically according to the desirable bias.

Results:

Of the analytes studied, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase (CK), gamma-glutamyl transferase (GGT), direct bilirubin, glucose, creatinine, cholesterol, triglycerides, high density lipoprotein (HDL) were stable in all conditions. Blood urea nitrogen (BUN), uric acid, total protein, albumin, total bilirubin, calcium, lactate dehydrogenase (LD) were changed significantly (P < 0.005).

Conclusions:

As a result, common clinical chemistry analytes, with considering the variability of unstable analytes, showed adequote stability after 3 months of storage in sera at −20 °C, or up to ten times of freeze-thaw cycle. All the same, such analysis can only be performed for exceptional cases, and this should be taken into account while planning studies.  相似文献   

The Assessment of Oxidative Stress on Patients with Chronic Renal Failure at Different Stages and on Dialysis Patients Receiving Different Hypertensive Treatment     

Servin Yeşil Günal  Bilal Üstündağ  Ali İhsan Günal 《Indian journal of clinical biochemistry : IJCB》2013,28(4):390-395

The aim of this study is to evaluate the oxidative stress in predialysis, hemodialysis (HD) and peritoneal dialysis patients and to test the effects of antihypertensive drugs and volume control on oxidative stress parameters. The study was composed of five groups as follows: control group (n = 30), predialysis group (n = 30), peritoneal dialysis group (n = 30), hemodialysis group, (normotensive with strict volume control, n = 30), hemodialysis group (normotensive with medication, n = 30). Plasma malondialdehyde (MDA), erythrocyte superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSHPx) and routine biochemical parameters were studied in all patients. Hemodialysis patients with strict volume control (HD_vc) had lower levels of MDA than other patient groups (p < 0.001), and CAT, SOD values had highest level other patient groups (p < 0.001). The treatment of hypertension with strict volume control in chronic renal failure patients causes less damage to the antioxidant capacity.  相似文献   

Higher Education as a Public Good: Means and Forms of Provision     

KLAUS HÜFNER 《Higher Education in Europe》2003,28(3):339-348

The question of whether or not higher education is a public good is discussed from three perspectives: the economic perspective, the legal perspective, and the normative-political perspective. As these perspectives overlap in many ways, the conclusion is that higher education is best described as a mixed good, one that is both public and private. Its efficiency of delivery would be increased by its being somewhat marketized.  相似文献   

An Academic Performance Measurement System and its Impact on Quality of Engineering Faculty Work at Middle East Technical University     

YILDIRIM ÜÇTUG  GÜLSER KÖKSAL 《Assessment & Evaluation in Higher Education》2003,28(3):251-262

A system has been developed for measuring the performance of faculty members at Middle East Technical University (METU) in 1998. This system has been designed to provide feedback for improving the quality of academic work. It involves a separate set of criteria and measures for each college within the university. The criteria used for the College of Engineering include publications, editorial work and translation, professional and other research activities, educational activities, memberships and awards, and other activities. Faculty members are recruited based on these criteria. They report their activities and works annually as required by this system, and they can access their measurement results through the university Intranet. These results play a significant role in promotion of the faculty members. Awards are given to faculty members who demonstrate superior performance. This system has also been utilised to measure the efficiency of engineering departments, and guide and support departments in improving their efficiency. Since the beginning of implementation of this system, significant changes have been observed in preferences and activities of faculty members, and their performance. The paper discusses impact of this system on performance of the Engineering College.  相似文献   

Changing policy contexts and teachers´ work-life narratives: the case of Estonian vocational teachers     

Ivor F. Goodson  Meril Ümarik 《Teachers and Teaching》2019,25(5):589-602

ABSTRACT

In recent decades, the work of teachers worldwide has undergone deep change. We have seen that teachers have encountered recent challenges differently and adapted to educational changes to a different extent depending on their personal disposition, but also school leadership and workplace support. This study focuses on the example of Estonian vocational teachers that serves as an interesting case for analysing how the interplay of the transitional context and neo-liberal policy trends adopted since Estonia regained its independence in 1991, after 50 years under Soviet rule, have affected the individual trajectories of teachers’ lives. This paper aims to understand how the interplay of the institutional context and individual (work) lives shapes Estonian vocational teachers’ understandings of their work and professionality. We suggest that certain periods of practice are visible in teachers’ narratives and those periods might be considered as enabling different degrees of agency. However, our interviews also revealed that different reform periods have been perceived and responded to differently. In the context of 25 years of the educational reform process, the policies and requirements introduced have been refracted at different levels (Goodson & Rudd, 2017), including that of the vocational field, the schools and individual teachers. Our results confirm that teachers individual, social, cultural and material resources such as competence, career stage, relations and networks, school leadership and prevailing culture at schools have their role in enabling or hindering the agency of teachers.  相似文献